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Becton Dickinson
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Becton Dickinson
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MultiSciences Biotech Co Ltd
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Becton Dickinson
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Merck KGaA
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Ubio Biotechnology Systems Pvt Ltd
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Becton Dickinson
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MabTag Inc
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Bioworld Antibodies
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Image Search Results
Journal: Signal Transduction and Targeted Therapy
Article Title: A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway
doi: 10.1038/s41392-020-0123-0
Figure Lengend Snippet: DCZ0858 induces cell apoptosis via caspase activation. a NU-DUL-1 and OCI-LY8 cells were treated with DCZ0858 for 48 h, double stained with annexin V-FITC/PI, and analyzed by flow cytometry. b NU-DUL-1 and OCI-LY8 cells were treated with Z-VAD-FMK and DCZ0858 for 48 h, and the cells were analyzed by flow cytometry. c Western blotting was used to analyze the expression levels of the caspase family proteins, namely, caspase-3, caspase-8, caspase-9, and the B-cell lymphoma family proteins (Bcl-2, Bax, and Bcl-xL). All values represent the mean ± SD of three sets of experimental data; * P < 0.05, ** P < 0.01, and *** P < 0.001
Article Snippet: The Annexin V/PI used for
Techniques: Activation Assay, Staining, Flow Cytometry, Western Blot, Expressing